|
rs1799752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not observe associations between hypertension and rs1799752 (<i>P</i>=0.422), rs699 (<i>P</i>=0.36), rs5186 (<i>P</i>=0.49), and rs1799998 (<i>P</i>=0.71).
|
31511791 |
2019 |
|
rs1415088003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Synergistic Effects of ACE Insertion/Deletion and GNB3 C825T Polymorphisms on the Efficacy of PDE-5 Inhibitor in Patients with Pulmonary Hypertension.
|
26821322 |
2016 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The allele frequency of AGT M235T differed significantly between group 1 (patients with simple renal cysts and hypertension) and normal individuals (p < 0.05).
|
23907112 |
2015 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Gene polymorphisms of adducin GLY460TRP, ACE I/D, AND AGT M235T in pediatric hypertension patients.
|
25262176 |
2014 |
|
rs4362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When the cohort was stratified by sex, ACE rs4362 and AGT rs699 showed significant associations with WMLs in men only (P = 0.01 and P = 0.03, respectively), and remained significant after controlling for hypertension.
|
24622918 |
2014 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The I/D gene polymorphism of the angiotensin-converting enzyme and M235T of angiotensinogen were ruled out as risk factors for hypertension.
|
23598646 |
2013 |
|
rs4305
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The MDR analysis demonstrated that the interaction between BMI and rs4305 increased the susceptibility to hypertension.
|
24015270 |
2013 |
|
rs4363
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Under a dominant model, rs4291 rs4335, rs4344, rs4353, rs4362, and rs4363 polymorphisms were associated with an increased risk of hypertension after adjusting for age, gender, BMI, triglycerides, alcohol consumption, and smoking.
|
23741507 |
2013 |
|
rs4305
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A polymorphism in ACE (rs4305) showed modest replication of association with increased hypertension (β: 0.06 mm Hg; SE: 0.01 mm Hg; meta-analysis: P=3.0×10(-5)).
|
21444836 |
2011 |
|
rs4291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four polymorphisms, located in the ACE (rs4291), angiotensinogen (rs5049) and (pro)renin receptor (rs2968915; rs5981008) genes were significantly associated with hypertension in two vascular disease populations of CAD (EUROPA) and cerebrovascular disease (PROGRESS; n = 3571).
|
21157371 |
2011 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Renin-angiotensin-aldosterone system (RAAS) polymorphisms such as the angiotensinogen-gene-M235T-, the angiotensin-conversion enzyme (ACE)-gene I/D- and the angiotensin-II-type 1-receptor-(AT1R)-A1166C-polymorphism have been implicated in renal insufficiency and hypertension.
|
19681973 |
2010 |
|
rs1156835126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
|
rs553520266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
|
rs746566272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
|
rs755506668
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Furthermore, an M235T variant of the angiotensinogen (AGT) gene has been associated with hypertension, an important risk factor for the development and progression of diabetic nephropathy.
|
18413162 |
2008 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We also screened angiotensinogen gene AGT M235T and angiotensin-converting enzyme insertion/deletion polymorphism ACE I/D and found an association between TT genotype and hypertension.
|
18758497 |
2008 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We studied the effects of the angiotensinogen T174M and M235T, angiotensin converting enzyme insertion/deletion (ACE I/D), and angiotensin II receptor 1 (AT1R) A1166C gene polymorphisms on the risk of hypertension among Hispanics.
|
18497458 |
2008 |
|
rs1042309696
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
|
18212314 |
2008 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
M235T polymorphism of the angiotensinogen gene and insertion/deletion polymorphism of the angiotensin-1 converting enzyme gene in essential arterial hypertension in Caucasians.
|
17448297 |
2007 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In Slovak population, M235T is associated with increased blood pressure and D allele of ACE gene is associated with MI, chronic CHD and DCM, rather than with hypertension.
|
17579251 |
2007 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
People who carried both ACE ID (or DD) and AGT M235T MT (or MM) had more risk to have hypertension.
|
16685579 |
2006 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A case-control association study was conducted to investigate a possible involvement of polymorphisms of three renin-angiotensin system genes: ACE (I/D and T-3892C), AGT (M235T and T174M), and AT1R (A1166C) in the early development of hypertension.
|
16876684 |
2006 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, no association was found between M235T polymorphism and insulin resistance or PAI-1 levels, but results indicate relationship between I/D polymorphism of the ACE gene and plasma PAI-1 levels in the early stage of hypertension.
|
16981142 |
2006 |
|
rs1415088003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of the study was to verify the hypothesis if the interaction between the G protein beta3 subunit (GNB3) C825T polymorphism and ACE I/D polymorphism could lead to the disclosure of increased activity of sodium-proton exchanger and hypertension.
|
16314202 |
2006 |